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Kristina Eriksson

Professor

Kristina Eriksson
Professor
kristina.eriksson@microbio.gu.se
+46 31-342 4761

Postal Address: Box 480, 40530 Göteborg
Visiting Address: Guldhedsgatan 10 , 41346 Göteborg


Department of Rheumatology a Inflammation Research at Institute of Medicine (More Information)
Box 480
405 30 Göteborg
0313421000
Fax: +46 31823925
Visiting Address: Medicinaregatan 3, plan 5 , 413 90 Göteborg

About Kristina Eriksson

Kristina Eriksson was born in Stockholm and graduated from Gothenburg University in 1989. She defended her thesis "HIV and mucosal immunity: Implications for vaccine development" in 1995 and then spent the next two years as a post-doc at Cambridge University. She became Associate Professor of Immunology in 2000 and was in 2006 awarded a Research Fellowship in Microbial Pathogenesis by the Swedish Research Council.

From April 1, 2009, she is professor of viral immune pathology at the Department of Rheumatology and Inflammation Research, Institute of Medicine. 

Research

My research project deals with the interplay between virus and the host´s immune system during infection. My working hypothesis is that herpesviruses and their human host have co-evolved during evolution leading to a symbiosis between the virus and the host’s immune system.

The aim of my research is therefore to investigate the interactions between virus and host during chronic herpesvirus infection. In addition, I am interested in identifying novel anti-viral treatments. For these purposes, I study:

  • The neuroimmune regulation of herpes simplex virus type 2 (HSV-2) infection, with special emphasis on the establishment of viral latency in the CNS. These studies are performed in mice, and involve the characterization of immune responses within the CNS and its role in controlling viral replication.
     
  • Host genetic factors that contribute to HSV-2 disease development. These studies are performed in HSV-2 infected humans who do, or do not, display symptoms of disease.
     
  • If herpesvirus infections can influence the development of allergy in young children. The relationship between herpesvirus infections and allergic sensitization is characterized in 18 month old children and we concomitantly assess the impact of these viruses on the developing immune system. An animal model has been established to further these studies on a mechanistic lever.
     
  • The use of endogenous and synthetic substances as anti-viral agents. The main goal is to be able to eradicate an already established chronic viral infection.

 

Latest publications

Antiviral activity of tannic acid modified silver nanoparticles: Potential to activate immune response in herpes genitalis
P. Orłowski, A. Kowalczyk, E. Tomaszewska, K. Ranoszek-Soliwoda, A. Węgrzyn et al.
Viruses, Journal article 2018
Journal article

Complement Opsonization Promotes Herpes Simplex Virus 2 Infection of Human Dendritic Cells
E. Crisci, R. Ellegard, S. Nystrom, E. Rondahl, L. Serrander et al.
Journal of Virology, Journal article 2016
Journal article

An innate antiviral pathway acting before interferons at epithelial surfaces
M. B. Iversen, L. S. Reinert, M. K. Thomsen, I. Bagdonaite, R. Nandakumar et al.
Nature Immunology, Journal article 2016
Journal article

HSV-2 regulates monocyte inflammatory response via the Fas/FasL pathway.
Malgorzata Krzyzowska, Piotr Baska, Piotr Orlowski, Robert Zdanowski, Anna Winnicka et al.
PloS one, Journal article 2013
Journal article

Showing 1 - 10 of 51

2019

2018

Antiviral activity of tannic acid modified silver nanoparticles: Potential to activate immune response in herpes genitalis
P. Orłowski, A. Kowalczyk, E. Tomaszewska, K. Ranoszek-Soliwoda, A. Węgrzyn et al.
Viruses, Journal article 2018
Journal article

2017

2016

Complement Opsonization Promotes Herpes Simplex Virus 2 Infection of Human Dendritic Cells
E. Crisci, R. Ellegard, S. Nystrom, E. Rondahl, L. Serrander et al.
Journal of Virology, Journal article 2016
Journal article

An innate antiviral pathway acting before interferons at epithelial surfaces
M. B. Iversen, L. S. Reinert, M. K. Thomsen, I. Bagdonaite, R. Nandakumar et al.
Nature Immunology, Journal article 2016
Journal article

2013

HSV-2 regulates monocyte inflammatory response via the Fas/FasL pathway.
Malgorzata Krzyzowska, Piotr Baska, Piotr Orlowski, Robert Zdanowski, Anna Winnicka et al.
PloS one, Journal article 2013
Journal article

Showing 1 - 10 of 51

Page Manager: Karin Allander|Last update: 9/19/2019
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