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Liesbeth Vandenput

Researcher

OverviewPublicationsUNDEFINEDUNDEFINEDUNDEFINED

Liesbeth Vandenput
Researcher
liesbeth.vandenput@medic.gu.se
+46 31-342 4830

Postal Address: Su sahlgrenska, 413 45 Göteborg
Visiting Address: Vita stråket 11, bv , 41345 Göteborg


Department of Internal Medicine and Clinical Nutrition at Institute of Medicine (More Information)
SU Sahlgrenska
413 45 Göteborg
0313421000
Fax: +46 317863101
Visiting Address: Vita stråket SU , 413 45 Göteborg

About Liesbeth Vandenput

Liesbeth Vandenput is an Associate Professor in experimental endocrinology at the Institute of Medicine, University of Gothenburg. After receiving her PhD at the KU Leuven, Belgium she moved to Gothenburg in 2005 to study sex steroid metabolism in relation to bone and body composition in population-based Swedish cohort studies. More recently, she focuses on the genetics of bone and sex steroid levels using genome-wide association studies. She has made a significant contribution to the bone research field, with 98peer-reviewed publications and over 9000 citations (September 2019).

Main Research Topics

Clinical studies investigating the importance and causality of circulating sex steroidsfor age-related common diseases such as osteoporosis and cardiovascular diseases.

Preclinical studies to evaluate to role of local sex steroid metabolism within target tissues for tissue-specific sex steroid action.

Funding

Swedish Research Council
ALF

Current Ph.D. students

Main supervisor
Hannah Colldén (2015 -)

Co-supervisor
Maria Nilsson, MD (2009 -)

Teaching

Course leader for the Degree Project in Medicine, LÄÄ110 (30 hec), term 10, program in medicine, University of Gothenburg

Research areas

Major publications

Serum DHEA and Its Sulfate Are Associated With Incident Fall Risk in Older Men: The MrOS Sweden Study
Claes Ohlsson, Maria Nethander, M. K. Karlsson, B. E. Rosengren, E. Ribom et al.
Journal of Bone and Mineral Research, 2018

Read the full text
on a web page

Low Testosterone, but Not Estradiol, Is Associated With Incident Falls in Older Men: The International MrOS Study
Liesbeth Vandenput, Dan Mellström, G. A. Laughlin, P. M. Cawthon, J. A. Cauley et al.
Journal of Bone and Mineral Research, 2017

Read the full text
on a web page

Low Serum DHEAS Predicts Increased Fracture Risk in Older Men: The MrOS Sweden Study
Claes Ohlsson, Maria Nethander, A. Kindmark, O. Ljunggren, Mattias Lorentzon et al.
Journal of Bone and Mineral Research, 2017

Read the full text
on a web page

High Serum SHBG Predicts Incident Vertebral Fractures in Elderly Men.
Liesbeth Vandenput, Dan Mellström, Andreas Kindmark, Helena Johansson, Mattias Lorentzon et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2016

Read the full text
on a web page

Comparisons of Immunoassay and Mass Spectrometry Measurements of Serum Estradiol Levels and Their Influence on Clinical Association Studies in Men
Claes Ohlsson, Maria E. Nilsson, Åsa Tivesten, Henrik Ryberg, Dan Mellström et al.
Journal of Clinical Endocrinology & Metabolism, 2013

Read the full text
on a web page

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
Karol Estrada, Unnur Styrkarsdottir, Evangelos Evangelou, Yi-Hsiang Hsu, Emma L Duncan et al.
Nature genetics, 2012

Read the full text
on a web page

Older men with low serum IGF-I have an increased risk of incident fractures: The MrOS Sweden study.
Claes Ohlsson, Dan Mellström, Daniel Carlzon, Eric Orwoll, Östen Ljunggren et al.
Journal of bone and mineral research, 2011

Read the full text
on a web page

Genetic determinants of serum testosterone concentrations in men.
Claes Ohlsson, Henri Wallaschofski, Kathryn L Lunetta, Lisette Stolk, John R B Perry et al.
PLoS genetics, 2011

Read the full text
on a web page

Latest publications

The gut microbiota is a major regulator of androgen metabolism in intestinal contents.
Hannah Colldén, Andreas Landin, Ville Wallenius, Erik Elebring, Lars Fändriks et al.
American journal of physiology. Endocrinology and metabolism, Journal article 2019
Journal article

Read the full text
on a web page

Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry
Y. H. Hsu, K. Estrada, E. Evangelou, C. Ackert-Bicknell, K. Akesson et al.
Journal of Bone and Mineral Research, Journal article 2019
Journal article

Read the full text
on a web page

Pubertal timing and adult fracture risk in men: A population-based cohort study.
Liesbeth Vandenput, Jenny Kindblom, Maria Bygdell, Maria Nethander, Claes Ohlsson
PLoS medicine, Journal article 2019
Journal article

Read the full text
on a web page

Evidence of a Causal Effect of Estradiol on Fracture Risk in Men.
Maria Nethander, Liesbeth Vandenput, Anna L Eriksson, Sara H Windahl, Thomas Funck-Brentano et al.
The Journal of clinical endocrinology and metabolism, Journal article 2019
Journal article

Read the full text
on a web page

Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men.
Anna-Lena Eriksson, John R B Perry, Andrea D Coviello, Graciela E Delgado, Luigi Ferrucci et al.
Journal of Clinical Endocrinology and Metabolism, Journal article 2018
Journal article

Read the full text
on a web page

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders
S. Ligthart, A. Vaez, U. Võsa, M. G. Stathopoulou, P. S. de Vries et al.
American Journal of Human Genetics, Journal article 2018
Journal article

Read the full text
on a web page

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
X. Jiang, P. F. O'Reilly, H. Aschard, Y. H. Hsu, J. B. Richards et al.
Nature Communications, Journal article 2018
Journal article

Read the full text
on a web page

Serum DHEA and Its Sulfate Are Associated With Incident Fall Risk in Older Men: The MrOS Sweden Study
Claes Ohlsson, Maria Nethander, M. K. Karlsson, B. E. Rosengren, E. Ribom et al.
Journal of Bone and Mineral Research, Journal article 2018
Journal article

Read the full text
on a web page

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.
Despoina Manousaki, Tom Dudding, Simon Haworth, Yi-Hsiang Hsu, Ching-Ti Liu et al.
American journal of human genetics, Journal article 2018
Journal article

Read the full text
on a web page

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
M. C. Zillikens, S. Demissie, Y. H. Hsu, L. M. Yerges-Armstrong, W. C. Chou et al.
Nature Communications, Journal article 2017
Journal article

Read the full text
on a web page

Major publications

Serum DHEA and Its Sulfate Are Associated With Incident Fall Risk in Older Men: The MrOS Sweden Study
Claes Ohlsson, Maria Nethander, M. K. Karlsson, B. E. Rosengren, E. Ribom et al.
Journal of Bone and Mineral Research, 2018

Read the full text
on a web page

Low Testosterone, but Not Estradiol, Is Associated With Incident Falls in Older Men: The International MrOS Study
Liesbeth Vandenput, Dan Mellström, G. A. Laughlin, P. M. Cawthon, J. A. Cauley et al.
Journal of Bone and Mineral Research, 2017

Read the full text
on a web page

Low Serum DHEAS Predicts Increased Fracture Risk in Older Men: The MrOS Sweden Study
Claes Ohlsson, Maria Nethander, A. Kindmark, O. Ljunggren, Mattias Lorentzon et al.
Journal of Bone and Mineral Research, 2017

Read the full text
on a web page

High Serum SHBG Predicts Incident Vertebral Fractures in Elderly Men.
Liesbeth Vandenput, Dan Mellström, Andreas Kindmark, Helena Johansson, Mattias Lorentzon et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2016

Read the full text
on a web page

Comparisons of Immunoassay and Mass Spectrometry Measurements of Serum Estradiol Levels and Their Influence on Clinical Association Studies in Men
Claes Ohlsson, Maria E. Nilsson, Åsa Tivesten, Henrik Ryberg, Dan Mellström et al.
Journal of Clinical Endocrinology & Metabolism, 2013

Read the full text
on a web page

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
Karol Estrada, Unnur Styrkarsdottir, Evangelos Evangelou, Yi-Hsiang Hsu, Emma L Duncan et al.
Nature genetics, 2012

Read the full text
on a web page

Older men with low serum IGF-I have an increased risk of incident fractures: The MrOS Sweden study.
Claes Ohlsson, Dan Mellström, Daniel Carlzon, Eric Orwoll, Östen Ljunggren et al.
Journal of bone and mineral research, 2011

Read the full text
on a web page

Genetic determinants of serum testosterone concentrations in men.
Claes Ohlsson, Henri Wallaschofski, Kathryn L Lunetta, Lisette Stolk, John R B Perry et al.
PLoS genetics, 2011

Read the full text
on a web page

Showing 41 - 50 of 99

2014

Serum Estradiol Levels are Inversely Associated with Cortical Porosity in Older Men
Liesbeth Vandenput, Mattias Lorentzon, D Sundh, Maria E. Nilsson, M. K. Karlsson et al.
Journal of Clinical Endocrinology and Metabolism, Journal article 2014
Journal article

Read the full text
on a web page

Serum estradiol associates with blood hemoglobin in elderly men; The MrOS Sweden Study
Catharina Lewerin, Herman Nilsson-Ehle, Stefan Jacobsson, Helena Johansson, Valter Sundh et al.
Journal of Clinical Endocrinology and Metabolism, Journal article 2014
Journal article

Read the full text
on a web page

Genome-wide association study for radiographic vertebral fractures: A potential role for the 16q24 BMD locus
L. Oei, K. Estrada, E. L. Duncan, C. Christiansen, C. T. Liu et al.
Bone, Journal article 2014
Journal article

Read the full text
on a web page

Does bone resorption stimulate periosteal expansion? A cross sectional analysis of β-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT.
John P Kemp, Adrian Sayers, Lavinia Paternoster, David M Evans, Kevin Deere et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Journal article 2014
Journal article

Read the full text
on a web page

Genetics of endocrine disorders in the era of genome-wide association studies.
Liesbeth Vandenput, Claes Ohlsson
Molecular and cellular endocrinology, Magazine article 2014
Magazine article

Read the full text
on a web page

Genome-wide association studies on serum sex steroid levels.
Liesbeth Vandenput, Claes Ohlsson
Molecular and cellular endocrinology, Journal article 2014
Journal article

Read the full text
on a web page

2013

Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders
Marcel den Hoed, Mattias Lorentzon, Liesbeth Vandenput, Claes Ohlsson
Nature Genetics, Journal article 2013
Journal article

Read the full text
on a web page

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
SI Berndt, Liesbeth Vandenput, John-Olov Jansson, Mattias Lorentzon, Claes Ohlsson
Nature Genetics, Journal article 2013
Journal article

Read the full text
on a web page

Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts
K. S. Vimaleswaran, D. J. Berry, C. Lu, E. Tikkanen, S. Pilz et al.
Plos Medicine, Journal article 2013
Journal article

Read the full text
on a web page

Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure.
Lavinia Paternoster, Mattias Lorentzon, Terho Lehtimäki, Joel Eriksson, Mika Kähönen et al.
PLoS genetics, Journal article 2013
Journal article

Read the full text
on a web page

Showing 41 - 50 of 99

Page Manager: Karin Allander|Last update: 9/19/2019
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