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Liesbeth Vandenput

Researcher

Liesbeth Vandenput
Researcher
liesbeth.vandenput@medic.gu.se
+46 31-342 4830

Postal Address: Su sahlgrenska, 413 45 Göteborg
Visiting Address: Vita stråket 11, bv , 41345 Göteborg


Department of Internal Medicine at Institute of Medicine (More Information)
SU Sahlgrenska
413 45 Göteborg
0313421000
Fax: +46 317863101
Visiting Address: Vita stråket SU , 413 45 Göteborg

About Liesbeth Vandenput

Liesbeth Vandenput is an Associate Professor in experimental endocrinology at the Institute of Medicine, University of Gothenburg. After receiving her PhD at the KU Leuven, Belgium she moved to Gothenburg in 2005 to study sex steroid metabolism in relation to bone and body composition in population-based Swedish cohort studies. More recently, she focuses on the genetics of bone and sex steroid levels using genome-wide association studies. She has made a significant contribution to the bone research field, with 98peer-reviewed publications and over 9000 citations (September 2019).

Main Research Topics

Clinical studies investigating the importance and causality of circulating sex steroidsfor age-related common diseases such as osteoporosis and cardiovascular diseases.

Preclinical studies to evaluate to role of local sex steroid metabolism within target tissues for tissue-specific sex steroid action.

Funding

Swedish Research Council
ALF

Current Ph.D. students

Main supervisor
Hannah Colldén (2015 -)

Co-supervisor

Maria Nilsson, MD (2009 -)

Teaching

Course leader for the Degree Project in Medicine, LÄÄ110 (30 hec), term 10, program in medicine, University of Gothenburg

Major publications

High Serum SHBG Predicts Incident Vertebral Fractures in Elderly Men.
Liesbeth Vandenput, Dan Mellström, Andreas Kindmark, Helena Johansson, Mattias Lorentzon et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2016

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
Karol Estrada, Unnur Styrkarsdottir, Evangelos Evangelou, Yi-Hsiang Hsu, Emma L Duncan et al.
Nature genetics, 2012

Genetic determinants of serum testosterone concentrations in men.
Claes Ohlsson, Henri Wallaschofski, Kathryn L Lunetta, Lisette Stolk, John R B Perry et al.
PLoS genetics, 2011

Latest publications

Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry
Y. H. Hsu, K. Estrada, E. Evangelou, C. Ackert-Bicknell, K. Akesson et al.
Journal of Bone and Mineral Research, Journal article 2019
Journal article

Evidence of a Causal Effect of Estradiol on Fracture Risk in Men.
Maria Nethander, Liesbeth Vandenput, Anna L Eriksson, Sara H Windahl, Thomas Funck-Brentano et al.
The Journal of clinical endocrinology and metabolism, Journal article 2019
Journal article

Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men.
Anna-Lena Eriksson, John R B Perry, Andrea D Coviello, Graciela E Delgado, Luigi Ferrucci et al.
Journal of Clinical Endocrinology and Metabolism, Journal article 2018
Journal article

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders
S. Ligthart, A. Vaez, U. Võsa, M. G. Stathopoulou, P. S. de Vries et al.
American Journal of Human Genetics, Journal article 2018
Journal article

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
X. Jiang, P. F. O'Reilly, H. Aschard, Y. H. Hsu, J. B. Richards et al.
Nature Communications, Journal article 2018
Journal article

Serum DHEA and Its Sulfate Are Associated With Incident Fall Risk in Older Men: The MrOS Sweden Study
Claes Ohlsson, Maria Nethander, M. K. Karlsson, B. E. Rosengren, E. Ribom et al.
Journal of Bone and Mineral Research, Journal article 2018
Journal article

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.
Despoina Manousaki, Tom Dudding, Simon Haworth, Yi-Hsiang Hsu, Ching-Ti Liu et al.
American journal of human genetics, Journal article 2018
Journal article

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
M. C. Zillikens, S. Demissie, Y. H. Hsu, L. M. Yerges-Armstrong, W. C. Chou et al.
Nature Communications, Journal article 2017
Journal article

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
M Carola Zillikens, Serkalem Demissie, Yi-Hsiang Hsu, Laura M Yerges-Armstrong, Wen-Chi Chou et al.
Nature communications, Journal article 2017
Journal article

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
Mariaelisa Graff, Robert A Scott, Anne E Justice, Kristin L Young, Mary F Feitosa et al.
PLoS genetics, Journal article 2017
Journal article

Major publications

High Serum SHBG Predicts Incident Vertebral Fractures in Elderly Men.
Liesbeth Vandenput, Dan Mellström, Andreas Kindmark, Helena Johansson, Mattias Lorentzon et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2016

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
Karol Estrada, Unnur Styrkarsdottir, Evangelos Evangelou, Yi-Hsiang Hsu, Emma L Duncan et al.
Nature genetics, 2012

Genetic determinants of serum testosterone concentrations in men.
Claes Ohlsson, Henri Wallaschofski, Kathryn L Lunetta, Lisette Stolk, John R B Perry et al.
PLoS genetics, 2011

Showing 1 - 10 of 97

2019

Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry
Y. H. Hsu, K. Estrada, E. Evangelou, C. Ackert-Bicknell, K. Akesson et al.
Journal of Bone and Mineral Research, Journal article 2019
Journal article

Evidence of a Causal Effect of Estradiol on Fracture Risk in Men.
Maria Nethander, Liesbeth Vandenput, Anna L Eriksson, Sara H Windahl, Thomas Funck-Brentano et al.
The Journal of clinical endocrinology and metabolism, Journal article 2019
Journal article

2018

Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men.
Anna-Lena Eriksson, John R B Perry, Andrea D Coviello, Graciela E Delgado, Luigi Ferrucci et al.
Journal of Clinical Endocrinology and Metabolism, Journal article 2018
Journal article

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders
S. Ligthart, A. Vaez, U. Võsa, M. G. Stathopoulou, P. S. de Vries et al.
American Journal of Human Genetics, Journal article 2018
Journal article

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
X. Jiang, P. F. O'Reilly, H. Aschard, Y. H. Hsu, J. B. Richards et al.
Nature Communications, Journal article 2018
Journal article

Serum DHEA and Its Sulfate Are Associated With Incident Fall Risk in Older Men: The MrOS Sweden Study
Claes Ohlsson, Maria Nethander, M. K. Karlsson, B. E. Rosengren, E. Ribom et al.
Journal of Bone and Mineral Research, Journal article 2018
Journal article

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.
Despoina Manousaki, Tom Dudding, Simon Haworth, Yi-Hsiang Hsu, Ching-Ti Liu et al.
American journal of human genetics, Journal article 2018
Journal article

2017

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
M. C. Zillikens, S. Demissie, Y. H. Hsu, L. M. Yerges-Armstrong, W. C. Chou et al.
Nature Communications, Journal article 2017
Journal article

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
M Carola Zillikens, Serkalem Demissie, Yi-Hsiang Hsu, Laura M Yerges-Armstrong, Wen-Chi Chou et al.
Nature communications, Journal article 2017
Journal article

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
Mariaelisa Graff, Robert A Scott, Anne E Justice, Kristin L Young, Mary F Feitosa et al.
PLoS genetics, Journal article 2017
Journal article

Showing 1 - 10 of 97

Page Manager: Karin Allander|Last update: 9/19/2019
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