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Our research organization

The Department of Internal Medicine and Clinical Nutrition is organized into several sections, each specialized on one specific field of research. In each section in turn features several research projects and principal investigators.

Centre for Bone and Arthritis Research

The Centre for Bone and Arthritis Research (CBAR) is an interdepartmental collaboration lead by Claes Ohlsson. It includes research groups from the Departments of Internal Medicine, Rheumatology and Inflammation Research and Community Medicine. It has been particularly successful in achieving a high international scientific level, successful funding and recruitment of promising young researchers.

https://cbar.gu.se/

Allergology

The Krefting Research Centre under the leadership of Jan Lötvall and Bo Lundbeck has rapidly expanded the output of allergology research, in particular regarding definition of clinically relevant asthma phenotypes. Additional aims of the research centre include an update of the prevalence and disease severity of the asthma syndrome and of determinants to disease. Special interest will be paid to the impact of rhinitis and rhino-sinusitis in asthma. A further area of research within the allergology group is airway hyperreactivity and its molecular mechanisms (lead by Eva Millqvist).

https://krefting.gu.se/

Endocrinology

The endocrinology section has a longstanding tradition of internationally competitive research in pituitary disease, particularly regarding the growth hormone (GH) /IGF-I axis. The scientific output includes clinical characterization of GH deficiency and its substitution therapy with GH (Bengt-Åke Bengtsson and Gudmundur Johannsson), the importance of IGF-I on ageing (Johan Svensson) and GH/IGF-I impact on the cardiovascular system and the brain (Jörgen Isgaard). Claes Ohlsson has been very successful at a top national and international level in building up a large research group around bone physiology, osteoporosis and inflammatory bone disease.
 

Gastroenterology

Two leading groups can be identified within the gastroenterology section. The first one focuses on the characterization of the pathogenesis and pathophysiology of disorders of gastrointestinal motility and perception, and develops and evaluates new treatment options for these disorders (Magnus Simrén and semi-retired Hasse Abrahamsson). The other group focuses on the enteric neural control of the mucosa, muscle and immune system as an approach for better understanding of common gastrointestinal disorders (Henrik Sjövall). Both these groups have been very successful in their output of scientific publications, funding and training of PhD students.

Respiratory Medicine

There are three predominant groups in respiratory medicine:

The lung immunology group focuses on the immunology of chronic lung diseases characterized by excess neutrophilic inflammation (Anders Linden). This research group has a translational profile and a unique position in the field of Th17 biology and pathology in the lungs.

The second group (headed by Jan Hedner) uses a wide approach to clarify prevalence, disease mechanisms, complications and risks associated with obstructive sleep apnoea (OSA). One result has been the development of a network of 24 European sleep laboratories reporting into a joint data base located at the University of Gothenburg for quality assessment and genetic studies in OSA.

The third group is headed by Sven Larsson who has devoted many years to research on chronic obstructive pulmonary disease, in particular aspects of energy expenditure, physical activity, muscular dysfunction and rehabilitation.

Haematology

The haematology section has traditionally focused on thrombocyte cell biology and clinical disorders (first headed by Jack Kutti and later by Hans Wadenvik and Bob Olsson). Other research areas include immunotherapy in chronic lymphatic leukaemia (P-O Andersson) and allogenic stem cell transplantation and immunotherapy in malignant haematological disease (Mats Brune).

Clinical nutrition

The research in clinical nutrition is focused on changes in energy balance and body composition. Rapid changes in energy balance (negative as well as positive) lead to ill health.

Functional body composition mirrors effects of eg growth, pregnancy, lactation, aging and illness on skeletal muscle and bone and energy stores. In the field of energy balance and body composition, our department featurs some of the leading researchers in Europe.

Close contacts with clinically active dieticians at Sahlgrenska University Hospital (SU) allow for easy access to patients with nutrition-related diseases. The area of nutritional epidemiology is growing and well connected with strong environments at our university. 

Our researchers use facilities for clinical, epidemiological and intervention studies on relationships between lifestyle and chronic diseases. In addition, we have the long experience and techniques needed to study important minerals and vitamins.

The section consists of several groups and principal investigators organized after their main research area:

  • Body composition
  • Nutrition
  • Energy metabolism
  • Epidemiology 

 

Page Manager: Karin Allander|Last update: 7/17/2019
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