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- Ulf Lerner
Ulf Lerner
Seniorforskare
Avd för invärtesmedicin och kliniskOm Ulf Lerner
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The novel cytotoxic polybisphosphonate osteodex decreases bone resorption by enhancing cell death of mature osteoclasts without affecting osteoclastogenesis of RANKL-stimulated mouse bone marrow
macrophages
Petra Henning, Anna Westerlund, Sofia Moverare-Skrtic, Catharina Lindholm, Marcela Marquez-Mendez, Sten Nilsson, Anders R. Holmberg, Ulf H Lerner
INVESTIGATIONAL NEW DRUGS - 2024 -
Vitamin A – a scoping review for Nordic nutrition Recommendations
2023
Thomas Olsen, Ulf H Lerner
Food and Nutrition Research - 2023 -
B4GALNT3 regulates glycosylation of sclerostin and bone
mass
Sofia Moverare-Skrtic, J. Voelkl, Karin H. Nilsson, Maria Nethander, T. T. D. Luong, I. Alesutan, Lei Li, Jianyao Wu, Karin L Horkeby, Marie K Lagerquist, A. Koskela, J. Tuukkanen, J. H. Tobias, Ulf H Lerner, Petra Henning, Claes Ohlsson
eBioMedicine - 2023 -
Osteoprotective effect by interleukin-4 (IL-4) on lipoprotein-induced
periodontitis
Jorge F. Lima Teixeira, Petra Henning, Fernando A. Cintra Magalhães, Glaucia Coletto-Nunes, Thais Floriano-Marcelino, Anna Westerlund, Sofia Movérare-Skrtic, Guilherme J.P.L. Oliveira, Ulf H Lerner, Pedro Paulo C. Souza
Cytokine - 2023 -
An atlas of genetic determinants of forearm
fracture.
Maria Nethander, Sofia Movérare-Skrtic, Anders Kämpe, Eivind Coward, Ene Reimann, Louise Grahnemo, Éva Borbély, Zsuzsanna Helyes, Thomas Funck-Brentano, Martine Cohen-Solal, Juha Tuukkanen, Antti Koskela, Jianyao Wu, Lei Li, Tianyuan Lu, Maiken E Gabrielsen, Reedik Mägi, Mari Hoff, Ulf H Lerner, Petra Henning, Henrik Ullum, Christian Erikstrup, Søren Brunak, Arnulf Langhammer, Tiinamaija Tuomi, Asmundur Oddsson, Kari Stefansson, Ulrika Pettersson-Kymmer, Sisse Rye Ostrowski, Ole Birger Vesterager Pedersen, Unnur Styrkarsdottir, Outi Mäkitie, Kristian Hveem, J Brent Richards, Claes Ohlsson
Nature genetics - 2023 -
Anemia is associated with increased risk of non-vertebral osteoporotic fractures in elderly men: the MrOS Sweden
cohort
Hallgerdur Lind Kristjansdottir, Dan Mellström, Peter Johansson, M. Karlsson, Liesbeth Vandenput, Mattias Lorentzon, Hans Herlitz, Claes Ohlsson, Ulf H Lerner, Catharina Lewerin
Archives of Osteoporosis - 2022 -
Phytocystatin CsinCPI-2 Reduces Osteoclastogenesis and Alveolar Bone
Loss
N. D. Leguizamon, R. S. de Molo, G. Coletto-Nunes, A. V. B. Nogueira, S. V. Rocha, D. M. Neo-Justino, A. Soares-Costa, P. S. Cerri, Ulf H Lerner, P. P. C. Souza, J. A. Cirelli
Journal of Dental Research - 2022 -
Stimulation of osteoclast formation and bone resorption by glucocorticoids: Synergistic interactions with the calcium regulating hormones parathyroid hormone and 1,25(OH)<inf>2</inf>-vitamin
D3
Petra Henning, H. Herschel Conaway, Ulf H Lerner
Vitamins and Hormones Vol 120 Parathyroid Hormone - 2022 -
Estradiol and RSPO3 regulate vertebral trabecular bone mass independent of each
other
Karin H. Nilsson, Jianyao Wu, Karin L. Gustafsson, Maha El Shahawy, A. Koskela, J. Tuukkanen, J. Tuckermann, Petra Henning, Ulf H Lerner, Claes Ohlsson, Sofia Movérare-Skrtic
American journal of physiology. Endocrinology and metabolism - 2022 -
Stimulation of Osteoclast Formation by Oncostatin M and the Role of WNT16 as a Negative Feedback
Regulator
P. P. C. de Souza, Petra Henning, Ulf H Lerner
International Journal of Molecular Sciences - 2022 -
WNT16 is Robustly Increased by Oncostatin M in Mouse Calvarial Osteoblasts and Acts as a Negative Feedback Regulator of Osteoclast Formation Induced by Oncostatin
M
Petra Henning, Sofia Moverare-Skrtic, Anna Westerlund, P. P. C. de Souza, T. Floriano-Marcelino, Karin H. Nilsson, Maha El Shahawy, Claes Ohlsson, Ulf H Lerner
Journal of Inflammation Research - 2021 -
Immunoglobulin G complexes without sialic acids enhance osteoclastogenesis but do not affect arthritis-mediated bone
loss.
Edina Sehic, Anna Westerlund, Marie K Lagerquist, Ulf H Lerner, Hans Carlsten, Petra Henning, Cecilia Engdahl
Scandinavian journal of immunology - 2021 -
Osteocyte- and late osteoblast-derived NOTUM reduces cortical bone mass in
mice
Karin H. Nilsson, Petra Henning, Maha El Shahawy, Jianyao Wu, A. Koskela, J. Tuukkanen, C. Perret, Ulf H Lerner, Claes Ohlsson, Sofia Moverare-Skrtic
American Journal of Physiology-Endocrinology and Metabolism - 2021 -
High platelet count is associated with low bone mineral density: The MrOS Sweden
cohort.
Hallgerdur Lind Kristjansdottir, Dan Mellström, P. Johansson, M. Karlsson, Liesbeth Vandenput, Mattias Lorentzon, Hans Herlitz, Claes Ohlsson, Ulf H Lerner, Catharina Lewerin
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 2021 -
RSPO3 is important for trabecular bone and fracture risk in mice and
humans
Karin H. Nilsson, Petra Henning, Maha El Shahawy, Maria Nethander, T. L. Andersen, C. Ejersted, Jianyao Wu, Karin L. Gustafsson, A. Koskela, J. Tuukkanen, P. P. C. Souza, J. Tuckermann, Mattias Lorentzon, Linda Engström-Ruud, T. Lehtimaki, J. H. Tobias, S. R. Zhou, Ulf H Lerner, J. B. Richards, Sofia Moverare-Skrtic, Claes Ohlsson
Nature Communications - 2021 -
An ARHGAP25 variant links aberrant Rac1 function to early-onset skeletal
fragility
R. E. Makitie, Petra Henning, Y. Jiu, A. Kampe, K. Kogan, A. Costantini, V. V. Valimaki, C. Medina-Gomez, M. Pekkinen, I. B. Salusky, C. Schalin-Jantti, M. K. Haanpaa, F. Rivadeneira, J. H. D. Bassett, G. R. Williams, Ulf H Lerner, R. C. Pereira, P. Lappalainen, O. Makitie
JBMR Plus - 2021 -
High Plasma Erythropoietin Predicts Incident Fractures in Elderly Men with Normal Renal Function: The MrOS Sweden
Cohort.
Hallgerdur Lind Kristjansdottir, Catharina Lewerin, Ulf H Lerner, Hans Herlitz, Peter Johansson, Helena Johansson, Magnus Karlsson, Mattias Lorentzon, Claes Ohlsson, Östen Ljunggren, Dan Mellström
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2020 -
Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and
Fractures
J. Zheng, W. Maerz, I. Gergei, M. Kleber, C. Drechsler, C. Wanner, V. Brandenburg, S. Reppe, K. M. Gautvik, C. Medina-Gomez, E. Shevroja, A. Gilly, Y. C. Park, G. Dedoussis, E. Zeggini, Mattias Lorentzon, Petra Henning, Ulf H Lerner, Karin H. Nilsson, Sofia Moverare-Skrtic, D. Baird, B. Elsworth, L. Falk, A. Groom, T. D. Capellini, E. Grundberg, Maria Nethander, Claes Ohlsson, G. D. Smith, J. H. Tobias
Journal of Bone and Mineral Research - 2019 -
Vitamin A decreases the anabolic bone response to mechanical loading by suppressing bone
formation
Vikte Lionikaite, Petra Henning, Christina Drevinge, Furqan A. Shah, Anders Palmquist, P. Wikström, Sara H Windahl, Ulf H Lerner
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2019 -
Activation of Toll-like receptor 2 induces B1 and B2 kinin receptors in human gingival fibroblasts and in mouse
gingiva
P. P. C. Souza, P. Lundberg, I. Lundgren, F. A. C. Magalhaes, C. M. Costa-Neto, Ulf H Lerner
Scientific Reports - 2019 -
Osteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus is associated with bone mineral density in
humans
Sofia Moverare-Skrtic, Karin H. Nilsson, Petra Henning, Thomas Funck-Brentano, Maria Nethander, F. Rivadeneira, G. C. Nunes, A. Koskela, J. Tuukkanen, J. Tuckermann, C. Perret, P. P. C. Souza, Ulf H Lerner, Claes Ohlsson
Faseb Journal - 2019 -
The critical interplay between bone resorbing and bone forming
cells
Ulf H Lerner, E. Kindstedt, P. Lundberg
Journal of Clinical Periodontology - 2019 -
Osteoporosis and skeletal dysplasia caused by pathogenic variants in
SGMS2
M. Pekkinen, P. A. Terhal, L. D. Botto, Petra Henning, R. E. Makitie, P. Roschger, A. Jain, M. Kol, M. A. Kjellberg, E. P. Paschalis, K. van Lassen, M. Murray, P. Bayrak-Toydemir, Maria K Magnusson, J. Jans, M. Kausar, J. C. Carey, P. Somerharju, Ulf H Lerner, V. M. Olkkonen, K. Klaushofer, J. C. M. Holthuis, O. Makitie
Jci Insight - 2019 -
NOTUM inhibition increases endocortical bone formation and bone
strength
Robert Brommage, J. Liu, P. Vogel, F. Mseeh, A. Y. Thompson, D. G. Potter, M. K. Shadoan, G. M. Hansen, S. Jeter-Jones, J. Cui, D. Bright, J. P. Bardenhagen, D. D. Doree, Sofia Moverare-Skrtic, Karin H. Nilsson, Petra Henning, Ulf H Lerner, Claes Ohlsson, A. T. Sands, J. E. Tarver, D. R. Powell, B. Zambrowicz, Q. Y. Liu
Bone Research - 2019 -
Glucocorticoids employ the monomeric glucocorticoid receptor to potentiate vitamin D3 and parathyroid hormone-induced
osteoclastogenesis.
H Herschel Conaway, Petra Henning, Antia Lie, Jan Tuckermann, Ulf H Lerner
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2019 -
Osteoclasts in Health and
Disease.
Ulf H Lerner
Pediatric endocrinology reviews : PER - 2019 -
Finding a Toll on the Route: The Fate of Osteoclast Progenitors After Toll-Like Receptor
Activation
P. P. C. Souza, Ulf H Lerner
Frontiers in Immunology - 2019 -
Activation of Shc1 allows oncostatin M to induce RANKL and osteoclast formation more effectively than leukemia inhibitory
factor
E. Persson, P. P. C. Souza, T. Floriano-Marcelino, H. H. Conaway, Petra Henning, Ulf H Lerner
Frontiers in Immunology - 2019 -
Porcupine inhibitors impair trabecular and cortical bone mass and strength in
mice
Thomas Funck-Brentano, Karin H. Nilsson, Robert Brommage, Petra Henning, Ulf H Lerner, A. Koskela, J. Tuukkanen, M. Cohen-Solal, Sofia Moverare-Skrtic, Claes Ohlsson
Journal of Endocrinology - 2018 -
WNT16 overexpression partly protects against glucocorticoid-induced bone
loss
Claes Ohlsson, Karin H. Nilsson, Petra Henning, Jianyao Wu, Karin L. Gustafsson, Matti Poutanen, Ulf H Lerner, Sofia Moverare-Skrtic
American Journal of Physiology-Endocrinology and Metabolism - 2018 -
Effects of retinoids on physiologic and inflammatory osteoclastogenesis in
vitro
Vikte Lionikaite, Anna Westerlund, H. H. Conaway, Petra Henning, Ulf H Lerner
Journal of leukocyte biology - 2018 -
Clinically relevant doses of Vitamin A decrease cortical bone mass in
mice
Vikte Lionikaite, Karin L. Gustafsson, Anna Westerlund, Sara H Windahl, A. Koskela, J. Tuukkanen, H. Johansson, Claes Ohlsson, H. Herschel Conaway, Petra Henning, Ulf H Lerner
Journal of Endocrinology - 2018 -
High Serum Serotonin Predicts Increased Risk for Hip Fracture and Nonvertebral Osteoporotic Fractures: The MrOS Sweden
Study.
Hallgerdur Lind Kristjansdottir, Catharina Lewerin, Ulf H Lerner, Ewa Waern, Helena Johansson, Daniel Sundh, Magnus Karlsson, Steve R Cummings, Henrik Zetterberg, Mattias Lorentzon, Claes Ohlsson, Dan Mellström
Journal of Bone and Mineral Research - 2018 -
Antibiotics with Interleukin-15 inhibition reduces joint inflammation and bone erosions but not cartilage destruction in Staphylococcus aureus-induced
arthritis.
Berglind Bergmann, Pernilla Jirholt, Petra Henning, Catharina Lindholm, Claes Ohlsson, Iain B McInnes, Ulf H Lerner, Inger Gjertsson
Infection and immunity - 2018 -
Inducible Wnt16 inactivation: WNT16 regulates cortical bone thickness in adult
mice.
Claes Ohlsson, Petra Henning, Karin H. Nilsson, Jianyao Wu, Karin L. Gustafsson, Klara Sjögren, Anna E Törnqvist, Antti Koskela, Fu-Ping Zhang, Marie Lagerquist, Matti Poutanen, Juha Tuukkanen, Ulf H Lerner, Sofia Movérare-Skrtic
The Journal of endocrinology - 2018 -
Bone Cell Activity in Clinical Prostate Cancer Bone Metastasis and Its Inverse Relation to Tumor Cell Androgen Receptor
Activity
A. Nordstrand, E. B. Ylitalo, E. Thysell, E. Jernberg, S. Crnalic, A. Widmark, A. Bergh, Ulf H Lerner, P. Wikstrom
International Journal of Molecular Sciences - 2018 -
The Crucial Role of the WNT System in Bone
Remodelling
D. Grigorie, Ulf H Lerner
Acta Endocrinologica - 2018 -
SNX10 gene mutation leading to osteopetrosis with dysfunctional
osteoclasts
E. L. Stattin, Petra Henning, J. Klar, E. McDermott, C. Stecksen-Blicks, P. E. Sandstrom, T. G. Kellgren, P. Ryden, G. Hallmans, T. Lonnerholm, A. Ameur, M. H. Helfrich, F. P. Coxon, N. Dahl, J. Wikstrom, Ulf H Lerner
Scientific Reports - 2017 -
Inhibition of the insulin-like growth factor-1 receptor potentiates acute effects of castration in a rat model for prostate cancer growth in
bone
A. Nordstrand, S. H. Bergstrom, E. Thysell, E. Bovinder-Ylitalo, Ulf H Lerner, A. Widmark, A. Bergh, P. Wikstrom
Clinical & Experimental Metastasis - 2017 -
Inhibition of lipopolysaccharide-induced osteoclast formation and bone resorption in vitro and in vivo by cysteine proteinase
inhibitors
F. Stralberg, A. Kassem, F. Kasprzykowski, M. Abrahamson, A. Grubb, Catharina Lindholm, Ulf H Lerner
Journal of Leukocyte Biology - 2017 -
Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing
osteoporosis
P. Liu, S. Lee, J. Knoll, A. Rauch, S. Ostermay, J. Luther, N. Malkusch, Ulf H Lerner, M. M. Zaiss, M. Neven, R. Wittig, M. Rauner, J. P. David, P. Bertolino, C. X. Zhang, J. P. Tuckermann
Cell Death and Differentiation - 2017 -
Toll-Like Receptor 2 Stimulation of Osteoblasts Mediates Staphylococcus Aureus Induced Bone Resorption and Osteoclastogenesis through Enhanced
RANKL
A. Kassem, Catharina Lindholm, Ulf H Lerner
Plos One - 2016 -
High plasma osteocalcin is associated with low blood haemoglobin in elderly men: the MrOS Sweden
Study
Catharina Lewerin, Helena Johansson, M. K. Karlsson, Mattias Lorentzon, Ulf H Lerner, Jenny Kindblom, Claes Ohlsson, Ulf Smith, Dan Mellström
Journal of Internal Medicine - 2016 -
Vitaminer och
benhälsa
Ulf H Lerner
Nordisk Nutrition - 2016 -
Betydelsen av vitamin K för benmassa och
frakturer
Ulf H Lerner
Osteoporosnytt - 2016 -
Toll-liknande receptorers betydelse för inflammatorisk
bennedbrytning
Ulf H Lerner
Best Practise/Rheumatology - 2016 -
Activation of dimeric glucocorticoid receptors in osteoclast progenitors potentiates RANKL induced mature osteoclast bone resorbing
activity
H. H. Conaway, Petra Henning, A. Lie, J. Tuckermann, Ulf H Lerner
Bone - 2016 -
Osteoblast differentiation is enhanced by a nano-to-micro hybrid titanium surface created by Yb:YAG laser
irradiation.
Eduardo Mariscal-Muñoz, Carlos A S Costa, Hewerson S Tavares, Jonas Bianchi, Josimeri Hebling, João P B Machado, Ulf H Lerner, Pedro P C Souza
Clinical oral investigations - 2016 -
Mechanical load, sex hormones, and bone
modeling
Sara H Windahl, Ulf H Lerner
Biological mechanisms of tooth movement. Vinod Krishnan, Ze'ev Davidovitch (eds.) - 2015 -
The bone-sparing effects of estrogen and WNT16 are independent of each
other
Sofia Movérare-Skrtic, Jianyao Wu, Petra Henning, Karin L. Gustafsson, Klara Sjögren, Sara H Windahl, A. Koskela, J. Tuukkanen, Anna E Börjesson, Marie K Lagerquist, Ulf H Lerner, F.P. Zhang, J.Å. Gustafsson, Matti Poutanen, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 2015 -
TLR5, a novel mediator of innate immunity-induced osteoclastogenesis and bone
loss
A. Kassem, Petra Henning, Bert Kindlund, Catharina Lindholm, Ulf H Lerner
Faseb Journal - 2015 -
Retinoid receptors in bone and their role in bone
remodeling
Petra Henning, H. H. Conaway, Ulf H Lerner
Frontiers in Endocrinology - 2015 -
Increased Eotaxin and MCP-1 Levels in Serum from Individuals with Periodontitis and in Human Gingival Fibroblasts Exposed to Pro-Inflammatory
Cytokines
E. A. Bostrom, E. Kindstedt, R. Sulniute, P. Palmqvist, M. Majster, C. K. Holm, S. Zwicker, R. Clark, S. Onell, I. Johansson, Ulf H Lerner, P. Lundberg
Plos One - 2015 -
A new WNT on the bone: WNT16, cortical bone thickness, porosity and
fractures.
Francesca Gori, Ulf H Lerner, Claes Ohlsson, Roland Baron
BoneKEy reports - 2015 -
High serum adiponectin is associated with low blood haemoglobin in elderly men: the Swedish MrOS
study
Catharina Lewerin, Helena Johansson, Ulf H Lerner, M.K Karlsson, Mattias Lorentzon, E Barrett-Connor, Ulf Smith, Claes Ohlsson, Dan Mellström
Journal of Internal Medicine - 2015 -
Porphyromonas gingivalis Stimulates Bone Resorption by Enhancing RANKL (Receptor Activator of NF-kappa B Ligand) through Activation of Toll-like Receptor 2 in
Osteoblasts
A. Kassem, Petra Henning, P. Lundberg, P. P. C. Souza, Catharina Lindholm, Ulf H Lerner
Journal of Biological Chemistry - 2015 -
The WNT system: background and its role in
bone.
Ulf H Lerner, Claes Ohlsson
Journal of internal medicine - 2015 -
Low holotranscobalamin and cobalamins predict incident fractures in elderly men: the MrOS Sweden
Study
Catharina Lewerin, Herman Nilsson-Ehle, Stefan Jacobsson, Helena Johansson, Valter Sundh, M K Karlsson, Östen Ljunggren, Mattias Lorentzon, J A Kanis, Ulf H Lerner, S R Cummings, Claes Ohlsson, Dan Mellström
Osteoporosis International - 2014 -
Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility
fractures.
Sofia Movérare-Skrtic, Petra Henning, Xianwen Liu, Kenichi Nagano, Hiroaki Saito, Anna E Börjesson, Klara Sjögren, Sara H Windahl, Helen H. Farman, Bert Kindlund, Cecilia Engdahl, Antti Koskela, Fu-Ping Zhang, Emma E Eriksson, Farasat Zaman, Ann Hammarstedt, Hanna Isaksson, Marta Bally, Ali Kassem, Catharina Lindholm, Olof Sandberg, Per Aspenberg, Lars Sävendahl, Jian Q Feng, Jan Tuckermann, Juha Tuukkanen, Matti Poutanen, Roland Baron, Ulf H Lerner, Francesca Gori, Claes Ohlsson
Nature Medicine - 2014 -
Low holotranscobalamin and cobalamins predict incident fractures in elderly men: the MrOS
Sweden.
Catharina Lewerin, Herman Nilsson-Ehle, Stefan Jacobsson, Helena Johansson, Valter Sundh, M K Karlsson, O Ljunggren, Mattias Lorentzon, J A Kanis, Ulf H Lerner, S R Cummings, Claes Ohlsson, Dan Mellström
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 2014 -
Osteoclast progenitor cells present in significant amounts in mouse calvarial osteoblast isolations and osteoclastogenesis increased by
BMP-2.
Susanne Granholm, Petra Henning, Catharina Lindholm, Ulf H Lerner
Bone - 2013 -
The role of cytokines in inflammatory bone
loss.
Pedro P C Souza, Ulf H Lerner
Immunological investigations - 2013 -
Vitamin a metabolism, action, and role in skeletal
homeostasis.
H Herschel Conaway, Petra Henning, Ulf H Lerner
Endocrine reviews - 2013 -
Cysteine proteinase inhibitors regulate human and mouse osteoclastogenesis by interfering with RANK
signaling.
Fredrik Strålberg, Petra Henning, Inger Gjertsson, Bert Kindlund, Pedro P C Souza, Emma Persson, Magnus Abrahamson, Franciszek Kasprzykowski, Anders Grubb, Ulf H Lerner
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2013 -
Inhibition of the insulin-like growth factor-1 receptor enhances effects of simvastatin on prostate cancer cells in co-culture with
bone.
Annika Nordstrand, Marie Lundholm, Andreas Larsson, Ulf H Lerner, Anders Widmark, Pernilla Wikström
Cancer microenvironment : official journal of the International Cancer Microenvironment Society - 2013 -
IL-4 and IL-13 inhibit IL-1 beta and TNF-alpha induced kinin B-1 and B-2 receptors through a STAT6-dependent
mechanism
P. P. C. Souza, A. B. Brechter, R. I. Reis, C. A. S. Costa, P. Lundberg, Ulf H Lerner
British Journal of Pharmacology - 2013 -
Low-dose prednisolone in early rheumatoid arthritis inhibits collagen type I degradation by matrix metalloproteinases as assessed by serum 1CTP--a possible mechanism for specific inhibition of radiological
destruction.
Inga-Lill Engvall, Björn Svensson, Annelies Boonen, Désirée van der Heijde, Ulf H Lerner, Ingiäld Hafström
Rheumatology (Oxford, England) - 2013 -
Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not
2.
Sara H Windahl, L Saxon, Anna E Börjesson, Marie Lagerquist, B Frenkel, Petra Henning, Ulf H Lerner, Gl Galea, Lb Meakin, Cecilia Engdahl, Klara Sjögren, Mc Antal, A Krust, P Chambon, LE Lanyon, Js Price, Claes Ohlsson
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2013 -
Activation of the liver X receptor-β potently inhibits osteoclastogenesis from lipopolysaccharide-exposed bone marrow-derived
macrophages.
Kirsten M Robertson Remen, Ulf H Lerner, Jan-Åke Gustafsson, Göran Andersson
Journal of leukocyte biology - 2013 -
Interleukin-4 and interleukin-13 inhibit the expression of leukemia inhibitory factor and interleukin-11 in
fibroblasts.
Pedro P C Souza, Py Palmqvist, Pernilla Lundberg, Inger Lundgren, Lennart Hänström, João A C Souza, H Herschel Conaway, Ulf H Lerner
Molecular immunology - 2012 -
Interleukin 15 Mediates Joint Destruction in Staphylococcus Aureus
Arthritis
Louise Henningsson, Pernilla Jirholt, Yalda Rahpeymai Bogestål, Tove Eneljung, Martin Adiels, Catharina Lindholm, I. McInnes, S. Bulfone-Paus, Ulf H Lerner, Inger Gjertsson
Journal of Infectious Diseases - 2012 -
High serum adiponectin predicts incident fractures in elderly men: Osteoporotic fractures in men (MrOS)
Sweden.
Helena Johansson, Anders Odén, Ulf H Lerner, Hans Jutberger, Mattias Lorentzon, Elizabeth Barrett-Connor, Magnus K Karlsson, Östen Ljunggren, Ulf Smith, Eugene McCloskey, John A Kanis, Claes Ohlsson, Dan Mellström
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2012 -
The gut microbiota regulates bone mass in
mice
Klara Sjögren, Cecilia Engdahl, Petra Henning, Ulf H Lerner, Valentina Tremaroli, Marie Lagerquist, Fredrik Bäckhed, Claes Ohlsson
Journal of Bone and Mineral Research - 2012 -
Retinoids stimulate periosteal bone resorption by enhancing the protein RANKL, a response inhibited by monomeric glucocorticoid
receptor.
H Herschel Conaway, Amir Pirhayati, Emma Persson, Ulrika Pettersson, Olle Svensson, Catharina Lindholm, Petra Henning, Jan Tuckermann, Ulf H Lerner
The Journal of biological chemistry - 2011 -
[Serotonin: a messenger between the brain/small intestine and the skeleton. Animal models strengthen the hypothesis about the role of serotonin in bone
formation].
Ulf H Lerner, Claes Ohlsson, Håkan Ahlman, Dan Mellström
Läkartidningen - 2011 -
Comparisons between the effects of calcitonin receptor-stimulating peptide and intermedin and other peptides in the calcitonin family on bone resorption and
osteoclastogenesis.
Susanne Granholm, Petra Henning, Ulf H Lerner
Journal of cellular biochemistry - 2011 -
Activation of liver X receptor (LXR) inhibits receptor activator of nuclear factor κB ligand (RANKL)-induced osteoclast differentiation in an LXRβ-dependent
mechanism.
Kirsten M Robertson Remen, Petra Henning, Ulf H Lerner, Jan-Åke Gustafsson, Göran Andersson
The Journal of biological chemistry - 2011 -
The neuropeptide VIP regulates the expression of osteoclastogenic factors in
osteoblasts.
Emma Persson, Ulf H Lerner
Journal of cellular biochemistry - 2011 -
Cytokine responses against periodontal infection: protective and destructive
roles.
Yen-Chun G Liu, Ulf H Lerner, Yen-Tung A Teng
Periodontology 2000 - 2010 -
Development of a novel poly bisphosphonate conjugate for treatment of skeletal metastasis and
osteoporosis.
Anders R Holmberg, Ulf H Lerner, Ayodele A Alayia, Mai Al-Mohanna, Chaker Adra, Marcela Marquez, Lennart Meurling, Sten Nilsson
International journal of oncology - 2010 -
Stimulation of IL-6 type of cytokines in gingival fibroblasts by Toll-like 2
receptors
PCC Souza, P Palmqvist, I Lundgren, A Lie, CM Costa-Neto, P Lundberg, Ulf H Lerner
Journal of dental research - 2010 -
Polymorphisms in the macrophage migration inhibitory factor gene and bone loss in postmenopausal
women.
Maria Swanberg, Fiona McGuigan, Kaisa K Ivaska, Paul Gerdhem, Ulf H Lerner, Richard Bucala, George Kuchel, Anne Kenny, Kristina Akesson
Bone - 2010 -
Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid
receptor.
Alexander Rauch, Sebastian Seitz, Ulrike Baschant, Arndt F Schilling, Anett Illing, Brenda Stride, Milen Kirilov, Vice Mandic, Andrea Takacz, Ruth Schmidt-Ullrich, Susanne Ostermay, Thorsten Schinke, Rainer Spanbroek, Mario M Zaiss, Peter E Angel, Ulf H Lerner, Jean-Pierre David, Holger M Reichardt, Michael Amling, Günther Schütz, Jan P Tuckermann
Cell metabolism - 2010 -
Nuclear androgen receptor staining in bone metastases is related to a poor outcome in prostate cancer
patients.
S Crnalic, E Hörnberg, P Wikström, Ulf H Lerner, A Tieva, O Svensson, A Widmark, A Bergh
Endocrine-related cancer - 2010 -
Retinoids inhibit differentiation of hematopoietic osteoclast
progenitors.
H Herschel Conaway, Emma Persson, Marie Halén, Susanne Granholm, Olle Svensson, Ulrika Pettersson, Anita Lie, Ulf H Lerner
The FASEB journal - 2009 -
Establishment and validation of an in vitro co-culture model to study the interactions between bone and prostate cancer
cells.
Annika Nordstrand, Jonas Nilsson, Ase Tieva, Pernilla Wikström, Ulf H Lerner, Anders Widmark
Clinical & experimental metastasis - 2009 -
Porphyromonas gingivalis (Pg) a possible link between impaired oral health and acute myocardial
infarction.
Anders Holmlund, Måns Hedin, Pirkko J Pussinen, Ulf H Lerner, Lars Lind
International journal of cardiology - 2009 -
IL-1beta and TNF-alpha regulate IL-6-type cytokines in gingival
fibroblasts.
P Palmqvist, P Lundberg, I Lundgren, L Hänström, Ulf H Lerner
Journal of dental research - 2008 -
[The skeletal protein osteocalcin is also an endocrine hormone. Possible significance for type 2 diabetes and the metabolic
syndrome]
Ulf H Lerner, Claes Ohlsson, Dan Mellström
Läkartidningen - 2008 -
Kinins and neuro-osteogenic
factors
Ulf H Lerner, E Persson, P Lundberg
Principles of bone biology. 3rd edition - 2008 -
Osteotropic effects by the neuropeptides calcitonin gene-related peptide, substance P and vasoactive intestinal
peptide.
Ulf H Lerner, E Persson
Journal of musculoskeletal & neuronal interactions - 2008 -
Expression of the calcitonin receptor, calcitonin receptor-like receptor, and receptor activity modifying proteins during osteoclast
differentiation.
Susanne Granholm, Pernilla Lundberg, Ulf H Lerner
Journal of cellular biochemistry - 2008 -
Kinin B1 and B2 receptor expression in osteoblasts and fibroblasts is enhanced by interleukin-1 and tumour necrosis factor-alpha. Effects dependent on activation of NF-kappaB and MAP
kinases.
Anna Bernhold Brechter, Emma Persson, Inger Lundgren, Ulf H Lerner
Bone - 2008 -
[SSRI ökar risken för osteoporos och
frakturer]
Ulf H Lerner, Claes Ohlsson, Dan Mellström
Läkartidningen - 2007 -
Osteoclast formation is strongly reduced both in vivo and in vitro in the absence of
CD47/SIRPalpha-interaction.
Pernilla Lundberg, Cecilia Koskinen, Paul A Baldock, Hanna Löthgren, Asa Stenberg, Ulf H Lerner, Per-Arne Oldenborg
Biochemical and biophysical research communications - 2007 -
Effects on osteoclast and osteoblast activities in cultured mouse calvarial bones by synovial fluids from patients with a loose joint prosthesis and from osteoarthritis
patients.
Martin K Andersson, Pernilla Lundberg, Acke Ohlin, Mark J Perry, Anita Lie, André Stark, Ulf H Lerner
Arthritis research & therapy - 2007 -
Bradykinin potentiates cytokine-induced prostaglandin biosynthesis in osteoblasts by enhanced expression of cyclooxygenase 2, resulting in increased RANKL
expression.
Anna Bernhold Brechter, Ulf H Lerner
Arthritis and rheumatism - 2007 -
Effects of prostaglandin E2 and lipopolysaccharide on osteoclastogenesis in RAW 264.7
cells.
H Kaneko, M Mehrotra, C Alander, Ulf H Lerner, C Pilbeam, L Raisz
Prostaglandins, leukotrienes, and essential fatty acids - 2007 -
Calcitonin inhibits osteoclast formation in mouse haematopoetic cells independently of transcriptional regulation by receptor activator of NF-{kappa}B and
c-Fms.
Susanne Granholm, Pernilla Lundberg, Ulf H Lerner
The Journal of endocrinology - 2007 -
Glucocorticoid regulation of osteoclast differentiation and expression of receptor activator of nuclear factor-kappaB (NF-kappaB) ligand, osteoprotegerin, and receptor activator of NF-kappaB in mouse calvarial
bones.
Charlotte Swanson, Mattias Lorentzon, H Herschel Conaway, Ulf H Lerner
Endocrinology - 2006 -
Inhibition of hormone and cytokine-stimulated osteoclastogenesis and bone resorption by interleukin-4 and interleukin-13 is associated with increased osteoprotegerin and decreased RANKL and RANK in a STAT6-dependent
pathway.
Py Palmqvist, Pernilla Lundberg, Emma Persson, Anders Johansson, Inger Lundgren, Anita Lie, H Herschel Conaway, Ulf H Lerner
The Journal of biological chemistry - 2006 -
Deletions of genes encoding calcitonin/alpha-CGRP, amylin and calcitonin receptor have given new and unexpected insights into the function of calcitonin receptors and calcitonin receptor-like receptors in
bone.
Ulf H Lerner
Journal of musculoskeletal & neuronal interactions - 2006 -
Inflammation-induced bone remodeling in periodontal disease and the influence of post-menopausal
osteoporosis.
Ulf H Lerner
Journal of dental research - 2006 -
Bone remodeling in post-menopausal
osteoporosis.
Ulf H Lerner
Journal of dental research - 2006 -
[Bone
remodeling]
Ulf H Lerner, Osten Ljunggren
Läkartidningen - 2006 -
Cytokine responses of human gingival fibroblasts to Actinobacillus actinomycetemcomitans cytolethal distending
toxin.
G N Belibasakis, A Johansson, Y Wang, C Chen, Teresa Lagergård, S Kalfas, Ulf H Lerner
Cytokine - 2005 -
The cytolethal distending toxin induces receptor activator of NF-kappaB ligand expression in human gingival fibroblasts and periodontal ligament
cells.
G N Belibasakis, A Johansson, Y Wang, C Chen, S Kalfas, Ulf H Lerner
Infection and immunity - 2005 -
Abundant secretion of bioactive interleukin-1beta by human macrophages induced by Actinobacillus actinomycetemcomitans
leukotoxin.
P Kelk, R Claesson, L Hänström, Ulf H Lerner, S Kalfas, A Johansson
Infection and immunity - 2005 -
Different cysteine proteinases involved in bone resorption and osteoclast
formation.
M Brage, M Abrahamson, V Lindström, A Grubb, Ulf H Lerner
Calcified tissue international - 2005 -
Stimulation of resorption in cultured mouse calvarial bones by
thiazolidinediones.
A M Schwab, S Granholm, E Persson, B Wilkes, Ulf H Lerner, H H Conaway
Endocrinology - 2005 -
Increased expression of interleukin-6 by vasoactive intestinal peptide is associated with regulation of CREB, AP-1 and C/EBP, but not NF-kappaB, in mouse calvarial
osteoblasts.
Emma Persson, Olga S Voznesensky, Yu-Feng Huang, Ulf H Lerner
Bone - 2005 -
The neuropeptide VIP potentiates IL-6 production induced by proinflammatory osteotropic cytokines in calvarial osteoblasts and the osteoblastic cell line
MC3T3-E1.
Emma Persson, Ulf H Lerner
Biochemical and biophysical research communications - 2005 -
[Serotonin reuptake inhibitors may increase the risk of
osteoporosis]
Ulf H Lerner
Läkartidningen - 2005 -
Interleukin-6 promoter polymorphism is associated with bone quality assessed by calcaneus ultrasound and previous fractures in a cohort of 75-year-old
women.
Anna Nordström, Paul Gerdhem, Helena Brändström, Fredrik Stiger, Ulf H Lerner, Mattias Lorentzon, Karl Obrant, Peter Nordström, Kristina Akesson
Osteoporosis international - 2004 -
Cysteine proteinases in osteoclast function and
recruitment
Ulf H Lerner, M Brage, M Ransjö, F Kasprzykowski, R Kasprzykowska, Z Grzonka, M Abrahamson, A Grubb
Biological mechanisms of tooth movement and craniofacial adaptation - 2004 -
NEW MOLECULES IN THE TUMOR NECROSIS FACTOR LIGAND AND RECEPTOR SUPERFAMILIES WITH IMPORTANCE FOR PHYSIOLOGICAL AND PATHOLOGICAL BONE
RESORPTION.
Ulf H Lerner
Critical reviews in oral biology and medicine - 2004 -
Osteoclastogenesis is decreased by cysteine proteinase
inhibitors.
Monica Brage, Anita Lie, Maria Ransjö, Franciszek Kasprzykowski, Regina Kasprzykowska, Magnus Abrahamson, Anders Grubb, Ulf H Lerner
Bone - 2004 -
Bone resorbing activity and cytokine levels in gingival crevicular fluid before and after treatment of periodontal
disease.
Anders Holmlund, Lennart Hänström, Ulf H Lerner
Journal of clinical periodontology - 2004 -
Family 2 cystatins inhibit osteoclast-mediated bone resorption in calvarial bone
explants.
H S Brand, Ulf H Lerner, A Grubb, W Beertsen, A V Nieuw Amerongen, V Everts
Bone - 2004 -
cDNA-arrays and real-time quantitative PCR techniques in the investigation of chronic Achilles
tendinosis.
Håkan Alfredson, Mattias Lorentzon, Stina Bäckman, Assar Bäckman, Ulf H Lerner
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 2003 -
TNF-alpha gene polymorphism and plasma TNF-alpha levels are related to lumbar spine bone area in healthy female Caucasian
adolescents
P. Wennberg, P. Nordstrom, R. Lorentzon, Ulf H Lerner, Mattias Lorentzon
Eur J Endocrinol - 2002 -
Calcium sensing receptor gene polymorphism, circulating calcium concentrations and bone mineral density in healthy adolescent
girls.
Mattias Lorentzon, R Lorentzon, Ulf H Lerner, P Nordström
European journal of endocrinology - 2001 -
Osteocalcin gene polymorphism is related to bone density in healthy adolescent
females.
A Gustavsson, P Nordström, R Lorentzon, Ulf H Lerner, Mattias Lorentzon
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 2000