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Madeleine Rådinger

Professor

Madeleine Rådinger
Professor , Avd-/sektionschef, bitr, inst
Akademisk grad: Docent,
madeleine.radinger@lungall.gu.se
031-786 6713

Postadress: Su sahlgrenska, 41345 Göteborg
Besöksadress: Vita stråket su , 41345 Göteborg


Avd för invärtesmedicin och klinisk nutrition vid Institutionen för medicin (Mer information)
SU Sahlgrenska
413 45 Göteborg
0313421000
Fax: 0 317863101
Besöksadress: Vita stråket SU , 413 45 Göteborg

Om Madeleine Rådinger

Title: PhD, Associate professor
Position: Senior Lecturer, Chairman of Krefting Research Centre

Madeleine Rådinger graduatedfrom the University of Gothenburg with an MSc degree in Molecular biology, and in2006 she received a PhD in Respiratory Medicine and Allergologyat the University of Gothenburg. After her PhD, she took on a 2.5 years postdoctoral position at the Laboratory of Allergic Diseases, National Institute of Allergic and Infection Diseases, the National Institute of Health (NIH), in Bethesda, USA. She returned to the University of Gothenburg in 2010 and in 2013, she became Associate professorin Immunology.

Forskning

Rådinger research focuses on increasing the understanding of the immune systemin subgroups of asthma, including the contribution of immune regulatory microRNAs. The ultimate goal is to identify molecular drivers linked to clinical features in asthma subgroups, for stratification for targeted therapy, diagnosis and potentially identification of new therapeutic targets.

Her research is funded by the VBG group Herman Krefting Foundation for Asthma and Allergy Research, the Swedish Research Council, the Swedish Heart and Lung foundation, the Swedish Foundation for Strategic Research and ALF.

Rådinger collaborates with several national and internationalm research groups studyingmimmunology, respiratory research and microRNA biology. In 2019, she was awarded the big grant from the Swedish association for allergy research (SFFA) and the Swedish Cancer-and Allergy Foundation environmental medical award for her research.

Gruppmedlemmar

Elisabeth Ax– Industrial PhD student together with AstraZeneca
Emma Boberg – PhD student
Carina Malmhäll – PhD/laboratory engineer
Jenny Calvén – postdoctoral research fellow
Julie Weidner – postdoctoral research fellow

Artiklar

– 2019 års Miljömedicinska pris tilldelas Docent Madeleine Rådinger
– Akademiliv - Madeleine Rådinger fick Svenska föreningen för Allergologis stora stipendium 2019

Utvalda pubilkationer

  1. Malmhäll C, Alawieh S, Lu Y, Sjöstrand M, Bossios A, Eldh M and Rådinger M. 2014. MicroRNA-155 is essential for TH2 mediated allergen-induced eosinophilic inflammation in the lung. J Allergy Clin Immuol. 2014 May;133(5):1429-38.
    The first study to describe a role for microRNA-155 in the regulation of type 2 mediated allergic eosinophilic inflammation in a mouse model of asthma.
     
  2. Johansson K, Malmhäll C, Ramos-Ramirez P and Rådinger M. 2017. MicroRNA-155 is a critical regulator of type 2 innate lymphoid cells and IL-33 signaling in experimental models of allergic airway inflammation. J Allergy Clin Immunol. 2017 Mar;139(3):1007-1016.
    This is the first study to describe a regulatory role for a microRNA in ILC2 functionality.
     
  3. Malmhäll C, Weidner J, Rådinger M. 2019. MicroRNA-155 expression suggests a sex disparity in innate lymphoid cells at the single-cell level. Cell Mol Immunol. 2019 Oct 10. doi: 10.1038/s41423-019-0303-4. 
    The first study to describe that human circulating ILCs express microRNA-155 and that this expression is higher in females. 

Senaste publikationer

microRNAs in asthma pathogenesis - from mouse to man
Julie Weidner, Carina Malmhäll, Madeleine Rådinger
Journal of Translational Genetics and Genomics, Forskningsöversiktsartikel 2019
Forskningsöversiktsartikel

Furry animal allergen component sensitization and clinical outcomes in adult asthma and rhinitis.
Bright I Nwaru, Shintaro Suzuki, Linda Ekerljung, Sigrid Sjölander, Roxana Mincheva et al.
The journal of allergy and clinical immunology. In practice, Artikel i vetenskaplig tidskrift 2019
Artikel i vetenskaplig tidskrift

MicroRNAs in type 2 immunity
Kristina Johansson, Julie Weidner, Madeleine Rådinger
Cancer Letters, Artikel i vetenskaplig tidskrift 2018
Artikel i vetenskaplig tidskrift

Lanosterol Synthase Regulates Human Rhinovirus Replication in Human Bronchial Epithelial Cells
Cristopher McCrae, A. Dzgoev, Marcus Ståhlman, J. Horndahl, R. Svard et al.
American Journal of Respiratory Cell and Molecular Biology, Artikel i vetenskaplig tidskrift 2018
Artikel i vetenskaplig tidskrift

No difference in human mast cells derived from peanut allergic versus non-allergic subjects
L. F. Larsen, N. Juel-Berg, A. Hansen, K. S. Hansen, E. N. C. Mills et al.
Immunity Inflammation and Disease, Artikel i vetenskaplig tidskrift 2018
Artikel i vetenskaplig tidskrift

Visar 21 - 30 av 42

2013

Toll-like receptor expression in severe asthma with chronic rhinosinusitis
Carina Malmhäll, Apostolos Bossios, Margareta Sjöstrand, Bo Lundbäck, Jan Lötvall et al.
EAACI International Severe Asthma Forum (ISAF 2012) Gothenburg, Sweden. 11-13 October 2012. Clinical and Translational Allergy, Konferensbidrag (offentliggjort, men ej förlagsutgivet) 2013
Konferensbidrag (offentliggjort, men ej förlagsutgivet)

2012

2011

Glycogen synthase kinase-3b is a prosurvival signal for the maintenance of human mast cell homeostasis
Madeleine Rådinger, D Smrz, DD Metcalfe, AM Gilfillan
Journal of Immunology, Artikel i vetenskaplig tidskrift 2011
Artikel i vetenskaplig tidskrift

Current update on eosinophilic lung diseases and anti-IL-5 treatment
Konstantinos Samitas, Madeleine Rådinger, Apostolos Bossios
Recent patents on anti-infective drug discovery, Forskningsöversiktsartikel 2011
Forskningsöversiktsartikel

2010

Glycogen synthase kinase 3beta activation is a prerequisite signal for cytokine production and chemotaxis in human mast cells.
Madeleine Rådinger, Hye Sun Kuehn, Mi-Sun Kim, Dean D Metcalfe, Alasdair M Gilfillan
Journal of immunology (Baltimore, Md. : 1950), Artikel i vetenskaplig tidskrift 2010
Artikel i vetenskaplig tidskrift

Visar 21 - 30 av 42

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