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Madeleine Rådinger

Universitetslektor

Madeleine Rådinger
Universitetslektor
Akademisk grad: Docent,
madeleine.radinger@lungall.gu.se

Postadress: Su sahlgrenska, 41345 Göteborg
Besöksadress: Vita stråket su , 41345 Göteborg


Avd för invärtesmedicin och klinisk nutrition vid Institutionen för medicin (Mer information)
SU Sahlgrenska
413 45 Göteborg
0313421000
Fax: 0 317863101
Besöksadress: Vita stråket SU , 413 45 Göteborg

Om Madeleine Rådinger

Title: PhD, Associate professor
Position: Senior Lecturer, Chairman of Krefting Research Centre

Madeleine Rådinger graduatedfrom the University of Gothenburg with an MSc degree in Molecular biology, and in2006 she received a PhD in Respiratory Medicine and Allergologyat the University of Gothenburg. After her PhD, she took on a 2.5 years postdoctoral position at the Laboratory of Allergic Diseases, National Institute of Allergic and Infection Diseases, the National Institute of Health (NIH), in Bethesda, USA. She returned to the University of Gothenburg in 2010 and in 2013, she became Associate professorin Immunology.

Forskning

Rådinger research focuses on increasing the understanding of the immune systemin subgroups of asthma, including the contribution of immune regulatory microRNAs. The ultimate goal is to identify molecular drivers linked to clinical features in asthma subgroups, for stratification for targeted therapy, diagnosis and potentially identification of new therapeutic targets.

Her research is funded by the VBG group Herman Krefting Foundation for Asthma and Allergy Research, the Swedish Research Council, the Swedish Heart and Lung foundation, the Swedish Foundation for Strategic Research and ALF.

Rådinger collaborates with several national and internationalm research groups studyingmimmunology, respiratory research and microRNA biology. In 2019, she was awarded the big grant from the Swedish association for allergy research (SFFA) and the Swedish Cancer-and Allergy Foundation environmental medical award for her research.

Gruppmedlemmar

Elisabeth Ax– Industrial PhD student together with AstraZeneca
Emma Boberg – PhD student
Carina Malmhäll – PhD/laboratory engineer
Jenny Calvén – postdoctoral research fellow
Julie Weidner – postdoctoral research fellow

Artiklar

– 2019 års Miljömedicinska pris tilldelas Docent Madeleine Rådinger
– Akademiliv - Madeleine Rådinger fick Svenska föreningen för Allergologis stora stipendium 2019

Utvalda pubilkationer

  1. Malmhäll C, Alawieh S, Lu Y, Sjöstrand M, Bossios A, Eldh M and Rådinger M. 2014. MicroRNA-155 is essential for TH2 mediated allergen-induced eosinophilic inflammation in the lung. J Allergy Clin Immuol. 2014 May;133(5):1429-38.
    The first study to describe a role for microRNA-155 in the regulation of type 2 mediated allergic eosinophilic inflammation in a mouse model of asthma.
     
  2. Johansson K, Malmhäll C, Ramos-Ramirez P and Rådinger M. 2017. MicroRNA-155 is a critical regulator of type 2 innate lymphoid cells and IL-33 signaling in experimental models of allergic airway inflammation. J Allergy Clin Immunol. 2017 Mar;139(3):1007-1016.
    This is the first study to describe a regulatory role for a microRNA in ILC2 functionality.
     
  3. Malmhäll C, Weidner J, Rådinger M. 2019. MicroRNA-155 expression suggests a sex disparity in innate lymphoid cells at the single-cell level. Cell Mol Immunol. 2019 Oct 10. doi: 10.1038/s41423-019-0303-4. 
    The first study to describe that human circulating ILCs express microRNA-155 and that this expression is higher in females. 

Senaste publikationer

microRNAs in asthma pathogenesis - from mouse to man
Julie Weidner, Carina Malmhäll, Madeleine Rådinger
Journal of Translational Genetics and Genomics, Forskningsöversiktsartikel 2019
Forskningsöversiktsartikel

Furry animal allergen component sensitization and clinical outcomes in adult asthma and rhinitis.
Bright I Nwaru, Shintaro Suzuki, Linda Ekerljung, Sigrid Sjölander, Roxana Mincheva et al.
The journal of allergy and clinical immunology. In practice, Artikel i vetenskaplig tidskrift 2019
Artikel i vetenskaplig tidskrift

MicroRNAs in type 2 immunity
Kristina Johansson, Julie Weidner, Madeleine Rådinger
Cancer Letters, Artikel i vetenskaplig tidskrift 2018
Artikel i vetenskaplig tidskrift

Lanosterol Synthase Regulates Human Rhinovirus Replication in Human Bronchial Epithelial Cells
Cristopher McCrae, A. Dzgoev, Marcus Ståhlman, J. Horndahl, R. Svard et al.
American Journal of Respiratory Cell and Molecular Biology, Artikel i vetenskaplig tidskrift 2018
Artikel i vetenskaplig tidskrift

No difference in human mast cells derived from peanut allergic versus non-allergic subjects
L. F. Larsen, N. Juel-Berg, A. Hansen, K. S. Hansen, E. N. C. Mills et al.
Immunity Inflammation and Disease, Artikel i vetenskaplig tidskrift 2018
Artikel i vetenskaplig tidskrift

Sepsis-Like Systemic Inflammation Induced by Nano-Sized Extracellular Vesicles From Feces
K. S. Park, J. Lee, C. Lee, H. T. Park, J. W. Kim et al.
Frontiers in Microbiology, Artikel i vetenskaplig tidskrift 2018
Artikel i vetenskaplig tidskrift

Visar 1 - 10 av 39

2019

microRNAs in asthma pathogenesis - from mouse to man
Julie Weidner, Carina Malmhäll, Madeleine Rådinger
Journal of Translational Genetics and Genomics, Forskningsöversiktsartikel 2019
Forskningsöversiktsartikel

Furry animal allergen component sensitization and clinical outcomes in adult asthma and rhinitis.
Bright I Nwaru, Shintaro Suzuki, Linda Ekerljung, Sigrid Sjölander, Roxana Mincheva et al.
The journal of allergy and clinical immunology. In practice, Artikel i vetenskaplig tidskrift 2019
Artikel i vetenskaplig tidskrift

2018

MicroRNAs in type 2 immunity
Kristina Johansson, Julie Weidner, Madeleine Rådinger
Cancer Letters, Artikel i vetenskaplig tidskrift 2018
Artikel i vetenskaplig tidskrift

Lanosterol Synthase Regulates Human Rhinovirus Replication in Human Bronchial Epithelial Cells
Cristopher McCrae, A. Dzgoev, Marcus Ståhlman, J. Horndahl, R. Svard et al.
American Journal of Respiratory Cell and Molecular Biology, Artikel i vetenskaplig tidskrift 2018
Artikel i vetenskaplig tidskrift

No difference in human mast cells derived from peanut allergic versus non-allergic subjects
L. F. Larsen, N. Juel-Berg, A. Hansen, K. S. Hansen, E. N. C. Mills et al.
Immunity Inflammation and Disease, Artikel i vetenskaplig tidskrift 2018
Artikel i vetenskaplig tidskrift

Sepsis-Like Systemic Inflammation Induced by Nano-Sized Extracellular Vesicles From Feces
K. S. Park, J. Lee, C. Lee, H. T. Park, J. W. Kim et al.
Frontiers in Microbiology, Artikel i vetenskaplig tidskrift 2018
Artikel i vetenskaplig tidskrift

2017

Visar 1 - 10 av 39

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