Rosie Perkins

Moderate variations in the human diet impact the gut microbiota in humanized

Marc Schöler, Rima Chakaroun, Harald Brolin, Ingrid Larsson, Rosie Perkins, Hanns-Ulrich Marschall, Robert Caesar, Fredrik Bäckhed
ACTA PHYSIOLOGICA - 2024

Low-grade intestinal inflammation two decades after pelvic

radiotherapy.

Sravani Devarakonda, Annika Thorsell, Per Hedenström, Sanghita Banerjee, Azar Rezapour, Lisen Heden, MEV Johansson, George M. H. Birchenough, Amelie Toft Morén, Karin Gustavsson, Viktor Skokic, Victor L Pettersson, F. Sjöberg, Marie Kalm, Mohammad Al Masri, Michaela Ekh, Henrik Fagman, Mats Wolving, Rosie Perkins, Rodrigo A Morales, Francisca Castillo, Eduardo J Villablanca, Ulf Yrlid, Karin Bergmark, Gunnar Steineck, Cecilia Bull
EBioMedicine - 2023

Cardiomyocyte-specific PCSK9 deficiency compromises mitochondrial bioenergetics and heart

function.

Marion Laudette, Malin Lindbom, Muhammad Arif, Mathieu Cinato, Mario Ruiz, Stephen Doran, Azra Miljanovic, Mikael Rutberg, Linda Andersson, Martina Klevstig, Marcus Henricsson, Per-Olof Bergh, Entela Bollano, Nay Aung, J. Gustav Smith, Marc Pilon, Tuulia Hyötyläinen, Matej Orešič, Rosie Perkins, Adil Mardinoglu, Malin Levin, Jan Borén
Cardiovascular research - 2023

Evolution of age-related mutation-driven clonal haematopoiesis over 20 years is associated with metabolic dysfunction in

obesity

Johanna C. Andersson-Assarsson, R. C. van Deuren, Felipe M. Kristensson, M. Steehouwer, Kajsa Sjöholm, Per-Arne Svensson, M. Pieterse, C. Gilissen, Magdalena Taube, Peter Jacobson, Rosie Perkins, H. G. Brunner, M. G. Netea, M. Peltonen, Björn Carlsson, A. Hoischen, Lena M S Carlsson
Ebiomedicine - 2023

Accelerated QT adaptation following atropine-induced heart rate increase in LQT1 patients versus healthy controls: A sign of disturbed

hysteresis.

Pia Dahlberg, Karl-Jonas Axelsson, Steen M Jensen, Gunilla Lundahl, Farzad Vahedi, Rosie Perkins, Lennart Gransberg, Lennart Bergfeldt
Physiological reports - 2022

Dynamics of the normal gut microbiota: A longitudinal one-year population study in

Sweden

Lisa M. Olsson, F. Boulund, Staffan Nilsson, Muhammad Tanweer Khan, Anders Gummesson, L. Fagerberg, L. Engstrand, Rosie Perkins, M. Uhlén, Göran Bergström, Valentina Tremaroli, Fredrik Bäckhed
Cell Host and Microbe - 2022

Expansion of mutation-driven haematopoietic clones is associated with insulin resistance and low HDL-cholesterol in individuals with

obesity

Rosanne van Deuren, Johanna Andersson, Felipe M. Kristensson, Marloes Steehouwer, Kajsa Sjöholm, Per-Arne Svensson, Marc Pieterse, Christian Gilissen, Magdalena Taube, Peter Jacobson, Rosie Perkins, Han Brunner, Mihai Netea, Markku Peltonen, Björn Carlsson, Alexander Hoischen, Lena M S Carlsson
bioRxiv - 2021

Microbial Imidazole Propionate Affects Responses to Metformin through p38 gamma-Dependent Inhibitory AMPK

Phosphorylation

Ara Koh, Louise Mannerås Holm, N. O. Yunn, P. M. Nilsson, S. H. Ryu, Antonio Molinaro, Rosie Perkins, J. Gustav Smith, Fredrik Bäckhed
Cell Metabolism - 2020

The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional

Study

Hao Wu, Valentina Tremaroli, Caroline Schmidt, Annika Lundqvist, Lisa M. Olsson, Manuela Krämer, Anders Gummesson, Rosie Perkins, Göran Bergström, Fredrik Bäckhed
Cell Metabolism - 2020

The MTH1 inhibitor TH588 is a microtubule-modulating agent that eliminates cancer cells by activating the mitotic surveillance

pathway

Nadia Gul, Joakim Karlsson, Carolina Tängemo, Sanna Linsefors, Samuel Tuyizere, Rosie Perkins, Chandu Ala, Zhiyuan V. Zou, Erik Larsson, M. O. Bergo, Per Lindahl
Scientific Reports - 2019

In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse

model

A. Carreras, L. S. Pane, R. Nitsch, K. Madeyski-Bengtson, M. Porritt, P. Akcakaya, A. Taheri-Ghahfarokhi, E. Ericson, M. Bjursell, M. Perez-Alcazar, F. Seeliger, M. Althage, R. Knoll, R. Hicks, L. M. Mayr, Rosie Perkins, D. Linden, Jan Borén, M. Bohlooly-Y, M. Maresca
Bmc Biology - 2019

Comparative analysis of obesity-related cardiometabolic and renal biomarkers in human plasma and

serum.

Meenu Rohin Rajan, Matus Sotak, Fredrik Barrenäs, Tong Shen, Kamil Borkowski, Nicholas J. Ashton, Christina Biörserud, Tomas L Lindahl, Sofia Ramström, Michael Schöll, Per Lindahl, Oliver Fiehn, John W Newman, Rosie Perkins, Ville Wallenius, Stephan Lange, Emma Börgeson
Scientific reports - 2019

Simplified Intestinal Microbiota to Study Microbe-Diet-Host Interactions in a Mouse

Model

Petia Kovatcheva-Datchary, S. Shoaie, S. Lee, Annika Wahlström, I. Nookaew, Anna Hallén, Rosie Perkins, J. Nielsen, Fredrik Bäckhed
Cell Reports - 2019

Microbially Produced Imidazole Propionate Impairs Insulin Signaling through

mTORC1

Ara Koh, Antonio Molinaro, Marcus Ståhlman, Muhammad Tanweer Khan, Caroline Schmidt, Louise Mannerås Holm, Hao Wu, Alba Carreras, Louise Olofsson, Per-Olof Bergh, V. Gerdes, A. Hartstra, M. de Brauw, Rosie Perkins, Max Nieuwdorp, Göran Bergström, Fredrik Bäckhed
Cell - 2018

Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in

silico

E. Mobarak, Liliana Håversen, M. Manna, Mikael Rutberg, Malin Levin, Rosie Perkins, T. Rog, I. Vattulainen, Jan Borén
Scientific Reports - 2018

An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in

Humans

A. Mardinoglu, Hao Wu, Elias Björnson, C. Zhang, A. Hakkarainen, S. M. Rasanen, S. Lee, Rosellina Margherita Mancina, Mattias Bergentall, K. H. Pietilainen, S. Soderlund, N. Matikainen, Marcus Ståhlman, Per-Olof Bergh, Martin Adiels, B. D. Piening, M. Graner, N. Lundbom, Kevin Jon Williams, Stefano Romeo, J. Nielsen, M. Snyder, M. Uhlen, Göran Bergström, Rosie Perkins, Hanns-Ulrich Marschall, Fredrik Bäckhed, M. R. Taskinen, Jan Borén
Cell Metabolism - 2018

Diabetes-associated microbiota in fa/fa rats is modified by Roux-en-Y gastric

bypass

Tulika Arora, F. Seyfried, Neil G. Docherty, Valentina Tremaroli, Carel W le Roux, Rosie Perkins, Fredrik Bäckhed
Isme Journal - 2017

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the

drug

Hao Wu, E. Esteve, Valentina Tremaroli, Muhammad Tanweer Khan, Robert Caesar, Louise Mannerås Holm, Marcus Ståhlman, Lisa M. Olsson, M. Serino, M. Planas-Felix, G. Xifra, J. M. Mercader, D. Torrents, R. Burcelin, W. Ricart, Rosie Perkins, J. M. Fernandez-Real, Fredrik Bäckhed
Nature Medicine - 2017

Metabolic effects of Lactobacillus reuteri DSM 17938 in people with type 2 diabetes: A randomized controlled

trial

Reza Mobini, Valentina Tremaroli, Marcus Ståhlman, F. Karlsson, Max Levin, Maria Ljungberg, Maja Sohlin, Helene Berteus Forslund, Rosie Perkins, Fredrik Bäckhed, Per-Anders Jansson
Diabetes Obesity & Metabolism - 2017

Microbiota-induced obesity requires farnesoid X

receptor

Ava Parseus, Nina Sommer, Felix Sommer, Robert Caesar, Antonio Molinaro, Marcus Ståhlman, Thomas U. Greiner, Rosie Perkins, Fredrik Bäckhed
Gut - 2017

ARAP2 promotes GLUT1-mediated basal glucose uptake through regulation of sphingolipid

metabolism

Aditi Chaudhari, Liliana Håversen, Reza Mobini, Linda Andersson, Marcus Ståhlman, Emma Lu, Mikael Rutberg, Per Fogelstrand, Kim Ekroos, Adil Mardinoglu, Malin Levin, Rosie Perkins, Jan Borén
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids - 2016

The gut microbiota modulates host energy and lipid metabolism in

mice

Vidya R. Velagapudi, Rahil Hezaveh, Christopher S. Reigstad, Peddinti V. Gopalacharyulu, Laxman Yetukuri, Sama Islam, Jenny Felin, Rosie Perkins, Jan Borén, Matej Oresic, Fredrik Bäckhed
Journal of Lipid Research - 2009

The assembly of lipid droplets and its relation to cellular insulin

sensitivity.

Pontus Boström, Linda Andersson, Lu Li, Rosie Perkins, Kurt Højlund, Jan Borén, Sven-Olof Olofsson
Biochemical Society transactions - 2009

Rosie Perkins

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